Modeling of Articular Cartilage Growth

Författare: Manda, K., Eriksson, 
Dokumenttyp: Konferens
Tillstånd: Accepterad
Tidskrift: 10th International Symposium on Biomechanics and Biomedical Engineering, 11-14th April, Berlin, Germany
År: 2012


The long term objective of the present work is to develop an analytical articular cartilage growth model by including more realistic knee condyle geometry and dynamic loading situations. A simplified 2D axisymmetric representation of the human femoral articular cartilage was developed. The cartilage was modeled as a biphasic fluid saturated porous medium and a spatially varying load was assumed on to the cartilage surface to represent the realistic loading situation in the joint. An algorithm was developed for growth of articular cartilage by considering two individually growing constituents (proteoglycans and collagens) in the solid matrix of cartilage. From this model, we want to investigate the effect of mechanical factors and role of metal implant on the growth of cartilage around the localized metal implant.